|
Product
|
Particle Size (in µm)
(Typical Values)
|
Composition
|
Benefits
|
Applications
|
|
D50
|
D90
|
|
Cellactose® 80
|
167
|
298
|
75 % Lactose Monohydrate
25 % Powdered Cellulose
|
- · Excellent compactibility and flowability
- · Perfectly suited for poorly compressible APIs
- · High adherence capacity to API
- · Ideal tablet surface for easy and economical coating
- · High adherence capacity may prevent segregation and improves content uniformity
|
- · Direct compression
- · Dry granulation (Roller compaction, slugging)
- · Capsule filling
|
|
MicroceLac® 100
|
141
|
261
|
75% Alpha-Lactose Monohydrate
25% Microcrystalline Cellulose
|
- · Excellent compactability and flowability
- · Ideal for poorly compactable APIs, e.g. herbal extracts
- · Ideal tablet surface for straight forward and economical coating
- · High adherence capacity prevents segregation and subsequently improves content uniformity
|
- · Direct compression
- · Dry granulation (Roller compaction, slugging)
- · Capsule filling
|
|
MicroceLac® Plus
|
75
|
134
|
35% Alpha-Lactose Monohydrate
65% Microcrystalline cellulose
|
- · Outstanding tabletability
- · Exceptional compressibility
- · High tablet hardness with very low friability even at high drug loads
- · Synergistic effect of the co-processing in terms of tabletability and flowability
- · No capping tendency
- · Very smooth tablet surface for easy and economical coating
- · Reduction in tablet size
|
- · Primarily designed for direct compression and continuous direct compression
- · Direct compression of difficult-to-process APIs
- · Formulations with high API content
- · Suitable for mini-tablets
- · Easy and economical coating
|
|
CombiLac®
|
176
|
283
|
70% Alpha-Lactose Monohydrate
20 % Microcrystalline Cellulose
10 % Native Corn Starch
|
- · Excellent compactibility
- · Excellent flowability
- · Fast, hardness-independent tablet disintegration for effective API release
- · Low friability
- · Overcomes individual ingredient compaction and handling limitations
|
- · Direct compression
- · ODT formulations
- · Dry granulation (Roller compaction, slugging)
|