L-Histidine*

USP, EP, BP, JP, ChP

• · mAb stabilization
• · Maintaining pH
• · Metal ion chelator
• · Aids in maintaining solubility of mAbs

L-Histidine HCL*

EP, BP, JP, ChP

L-Arginine*

USP, EP, JP

· Prevent protein aggregation

· Enhance solubility of proteins

· Stabilize protein structures

· Viscosity reduction

· Lyophilization aid

L-Arginine HCL*

USP, EP, JP

• · Component of cell culture media
• · Facilitates refolding of proteins
• · Protein stabilizer in formulations

L-Methionine*

USP, EP, BP, JP, ChP

• · Antioxidant
• · Metal chelation

L-Glutamine

USP, JP, ChP

• · Parenteral Formulation
• · Liquid Formulation
• · Pharmaceutical Process
• · Biopharma Process
• · Upstream Protein Production
• · Upstream Feeds

Glycine

USP EP BP JP ChP

• · Protein stabilization
• · Buffering agent
• · Lyophilisation aid
• · Osmolality adjuster